THIS PRODUCT IS FOR RESEARCH PURPOSES ONLY.

+ Description

Ace-031, also known as ACVR2B, is a soluble form of activin type IIB receptor, which is an inhibitor of myostatin and other naturally occurring proteins that limit muscle growth. This compound was genetically developed to bind to myostatin before it can attach to its receptor and halt muscle growth. The two Biopharma companies that worked on this compound are Acceleron and Shire.

GHRP-2 is a sterile, non-pyrogenic, white lyophilized powder intended for subcutaneous or intramuscular injection, after reconstitution with sterile Water for Injection (0,3% m-Cresol).

+ Mechanism of action

ACE-031 is a protein that‘s being investigated to determine if it can be used for therapeutical purpose for building muscle and enhancing the strengh of test subjects. It does this by allowing molecules to bind to cell surface receptors – this is also where it signals through.

These cell surface receptors are known as Activin Receptor Type II B. ACE-031 is recombinant fusion protein that is produced when a portion of the ACVR2B receptor and a part of the standart antibody are joined together. This then creates a decoy version of ACVR2B that circulates and eliminates proteins like GDF-8 (alsno known as myostatin) and other molecules that limit the muscle‘s strength of growth.

The proteins in the TGF-8 superfamily are used to regulate muscle growth. These act as the on and off switch for the production of muscles. In order to stop muscle growth , several molecules, such as GDF-8, intermingle with the ACVR2B receptor, which stops the production of muscle. When these off switches aren‘t present , the muscle increase in mass radically.

+ Adverse reaction

ACE-031 could have the following side effects:

• Water Retention
• Bleeding from the nose
• Increased Hunger
• Headache
• Reactions at injection site

+ Instructions for reconstitution

The injection is given into the sub-cutaneous layer which includes adipose tissue (fat).

If you are using insulin syringes which have short needles, you will need to enter the skin at 90°. to the skin, otherwise you can inject as shown in the illustration above with a 29 or 30 gauge, 0.5" needle.

+ Dosage

Recommended dosage of ACE-031: 500 – 1.000 mcg twice a week

+ Storage

• This product can be used not more than 3 years from the production date (see box).
• After reconstitution, may be stored for a maximum of 14 days in a refrigirator at 2°C – 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.