THIS PRODUCT IS FOR RESEARCH PURPOSES ONLY.

+ Description

Sermorelin Acetate is a "growth hormone-releasing hormone" (GHRH). This prescription drug is compounded by U.S. pharmacies pursuant to a physician's prescription and is patient self-injected subcutaneously.

It stimulates the pituitary gland to naturally produce increased amounts of human growth hormone. Sermorelin Acetate is a truncated analog of a growth hormone releasing factor (GRF 1-44) that is naturally produced by the brain to stimulate pituitary production of human growth hormone. The increased volume of human growth hormone (hGH) produced by the pituitary gland causes an increase in the production of Insulin-Like Growth Factor-1 (IGF-1) by the liver and results in the benefits of treatment provided to the adult patient.

Sermorelin Acetate is a sterile, non-pyrogenic, white lyophilized powder intended for subcutneous or intramuscular injection, after reconstitution with sterile Water for Injection (0,3% m-Cresol).

+ Mechanism of action

As a result of Sermorelin Growth Hormone (GHRH) Therapy, the increased volume of human growth hormone (hGH) secreted by the stimulated pituitary gland is converted by the liver into IGF-1.

The increased amount of IGF-1 in the blood stream results an increase in metabolism and growth of new cells within the body's organs and bones. This treatment is prescribed for unlabeled use in adults to increase lean muscle mass, reduce body fat, increase bone density, enhance the immune system, and strengthen the heart, as well as, other organs of the body. Since the increased volume of human growth hormone is produced by the body's pituitary gland, the body's endocrine system will not allow more growth hormone to be produced by the Sermorelin GH-RH stimulation of the pituitary than the body can safely process within the endocrine self-monitoring system.

Sermorelin Acetate Growth Hormone - Releasing Hormone has been specifically approved for medical use in increasing growth hormone levels in children deficient in growth hormone production. Its use to increase the growth hormone and IGF-1 levels in adults is an off-label use of this prescription drug.

Sermorelin Acetate Growth Hormone - Releasing Hormone Therapy causes the pituitary gland to increase the growth hormone and IGF-1 levels in humans. It is a prescription drug approved for one medical use that may be prescribed for adults for other unlabeled medical uses that are determined by the treating physician to be indicated and appropriate.

Sermorelin therapy or recombinant human growth hormone therapy include the following:

• Increases the development of lean body mass through the development of new muscle cells
• Reduces body fat through lipolysis
• Increases energy and vitality
• Increases strength
• Increases endurance
• Accelerates healing from wounds or surgery
• Strengthens the heart
• Enhances the immune system
• Increases IGF-1 production
• Improves sleep quality
• Increases calcium retention, and strengthens and increases the mineralization of bone or bone density.
• Increases protein synthesis and stimulates the growth of all internal organs except the brain.

+ Adverse reaction

• Hives
• Difficulty Swallowing
• Dizzy
• Temporary Redness of Face and Neck
• Head Pain
• Nervouse

+ Instructions for reconstitution

The injection is given into the sub-cutaneous layer which includes adipose tissue (fat).

If you are using insulin syringes which have short needles, you will need to enter the skin at 90°. to the skin, otherwise you can inject as shown in the illustration above with a 29 or 30 gauge, 0.5" needle.

+ Dosage

Recommended dosage of Sermorelin Acetate: 200 – 500 mg once per day.

+ Storage

• This product can be used not more than 3 years from the production date (see box).
• After reconstitution, may be stored for a maximum of 14 days in a refrigerator at 2°C – 8°C.
• Store vials in an upright position.
• Store in a refrigerator (2°C – 8°C). Keep in the outer carton in order to protect from light.
• For one month can be stored at room temperature.