Tamoxifen Sopharma is the same drug like Nolvadex but much cheaper. This is original pharmaceutical product that contains 10 miligrams Tamoxifen citrate in 1 pill.

The compound was first created in 1961 by ICI now AstraZeneca. The compound was developed to treat breast cancer, specifically hormone-responsive breast cancer. It still be prescribed for effective treatment and breast cancer prevention.

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Tamoxifen mechanism of action

Tamoxifen is an effective Selective Estrogen Receptor Modulator (SERM) that is referred to as an anti-estrogen. However, while being an antagonist it is also an agonist as it will actually act as estrogen in certain parts of the body while acting as an anti-estrogen in other areas. As one of the oldest SERM on the market that is still regularly used medicinally. Tamoxifen is also used by anabolic steroid users but it is not an anabolic steroid. This is an important note as some are often confused by its use in steroid cycles. Tamoxifen is simply a SERM which is an essential part of the bodybuilding.

Not long after the users of anabolic steroids discovered that the compound is very important for them! It can be used as an anti-estrogen during an anabolic steroid cycle in order to prevent estrogenic related side effects. Tamoxifen is also used as part of a Post Cycle Therapy (PCT) recovery plan, which is its most common and beneficial point of use for the steroid user.

Tamoxifen effects

For the breast cancer patient, the effect of the drug is straightforward. By blocking the estrogen from attaching the cancer will not be unable to feed on the hormone to its survival.

For the anabolic steroid user, the primary effect of Tamoxifen on steroid cycle is in the prevention of gynecomastia. The compound does not appear to have a strong effect in preventing the other primary estrogenic effect in water retention, but this can often be controlled in other ways. As for gynecomastia protection, this can be enough for many men and should be your first choice if it can get the job done. If not, you will need more powerfull AI (Aromatase Inhibitor) like Arimidex (Anastrozole). However, AI’s can have a negative effect on cholesterol. Alone AI’s do not appear to have a strong, negative effect, but when coupled with an aromatizing steroid this effect appears to be exasperated. Cholesterol can be controlled with the use of an AI, but if it can get the job done a SERM like Tamoxifen should be your first choice. As an added bonus, remember this SERM will have a positive impact on your cholesterol levels.

Another valuable feature of Tamoxifen for a bodybuilder is his effect to increase the natural body testosterone production. Although primarily the drug is an anti-estrogen, it also possess strong testosterone stimulating characteristics. Tamoxifen has the ability to block the negative feedback that is brought on by estrogen at the hypothalamus and pituitary. As a result, this stimulates an enhanced release by the pituitary of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH). Both LH and FSH are essential to natural testosterone production. Without LH and FSH, with an even stronger emphasis on LH, there is no natural testosterone production.

Due to the low testosterone issues after a cycle of anabolic steroids, most men are encouraged to implement a PCT plan that includes Tamoxifen. Many PCT plans often contain Tamoxifen-citrate as well as the SERM Clomid (Clomiphene Citrate) and the powerful peptide hormone HCG (Human Chorionic Gonadotropin). By implementing this PCT plan, you will greatly stimulate natural testosterone production, speed up the recovery process and greatly protect your physique. Once the PCT plan comes to an end, contrary to popular belief your testosterone levels will not be resting at their normal high level state. Total recovery will still take a lot of time. However, a PCT plan that includes Tamoxifen-citrate will ensure you have enough testosterone for proper bodily function while your levels continue to naturally rise.

Tamoxifen Dosage

During an anabolic steroid cycle:
for the purpose of estrogenic side effect protection, 10-20 mg per day is common. If 20 mg per day does not protect you from gynecomastia you will need an AI (Aromatase Inhibitor). If you cannot control water retention with this dose you may also need to consider an AI, but with a sound diet that is not over abundant in calories, especially carbohydrates, water retention should be controlled.

Tamoxifen Dosage in Post Cycle Therapy (PCT):
for the purpose of PCT, standard doses will normally begin at 30-40 mg per day. The dose will normally hold at 40 mg per day for a couple weeks, then reduce to 20 mg per day for a week and then finish with an optional week at 10 mg per day. But if you combine it with Clomid and / or HCG, then dose must be reduced at half.

If your cycle ends with any large ester base anabolic steroids (such as Enanthate, Decanoate, Cypionate ..), you must begin tamoxifen 2 weeks after your last injection.

If your cycle ends with all small ester base anabolic steroids (such as Propionate, Phenylpropionate, Acetate ..), you must begin administration 3 days after your last injection.

Tamoxifen Side Effects

When using this drug it's possible to occur some adverse reactions, but we will find that the compound is well tolerated by most men and women. However, there are some side effects, but they are usually very rare. Most men will not have any problem. The side effects of the compound will be slightly more common in women, but even then they are not all that common. possible side effects of Tamoxifen use include:

• Vaginal Itching, bleeding, discharge or discomfort
• Hot Flashes
• Upset Stomach
• Headaches

As a final note, women who are pregnant or who may become pregnant should not for any reason take Tamoxifen. Such use can potentially be very damaging to the developing child.

Is Tamoxifen Hepatoxic?

The compound is metabolized by the liver - so can be hepatotoxicity? However, tamoxifen has been shown to protect against alcohol-induced liver damage and estrogen-related hepatic injury (xeno-estrogens, etc.). It's pretty safe compound within the bounds of it's prescribed dosing range. There's no interaction with alcohol or AAS. The only real danger would be huge doses and prolonged exposure, much as anything else that would cause permanent liver damage.